Putting this here because I like this thread more than the crafting announcement one.
I agree with Brosgw that the answer is almost certainly going to be a hard no, which for me is a problem with the new system. Being able to change perks and blessings on the fly without locks is a large positive change, but it seems that will be more for if you are changing your build, not if you want to use the same weapon on multiple different builds.
This is why the system is still worse than a more traditional loadout system imo. If instead of acquiring individual weapons, you just got it access to it during the character level up process and than unlocked perks and blessings for it with Mastery (I think I’m using that term correctly), you wouldn’t have to grind up the same weapon for different builds.
Also would remove any issues with grinding for good base stats or good maximum potential stats (if that’s a thing?).