For me, every game since I got a GTX 1660 super I have to go and turn off Motion Blur and save changes. When I reopen the game it is automatically turned back on.
I am using the by-pass launcher option when I launch the game, as it doesn’t always close properly and leaves VT2 appearing in steam as running, when it’s not.
I’ve had this happen to me, then I realised I’d changed the graphics profile in the loader, so every time I loaded up the game the profile overwrote the custom settings I’d changed previously. Make sure your graphics setting is on “custom” in the game loader settings, then see if turning motion blur off in game sticks.