I think that game balance doesn’t lend itself to that kind of thing in its current state. You have things that are totally OP like a psyker aura that refills everyones ability for killing a couple elites, coupled with abilities that make you immune to damage and can be spammed with absurd uptime.
To really explain what I mean: there is another thread where someone came up with a lot of fun mutator concepts:
It’s an excellent thread and I think it nails the idea of “add interesting mutators instead of just tweaking numbers” perfectly. However…
I dare you to find literally a single combination of mutators the OP came up here that wouldn’t be completely trivialized by VoC spam and turn the game into just a regular damnation game anyway. Obviously no shade on the guy who wrote it, I found it a fun read, but it’s simply that the game balance wouldn’t allow for any of it to be actually challenging. Slower abilities? Psykinetics aura. Gunners slow you? Spam walls or have such high mobility it never matters in the first place. Bosses spawn with a patrol? Cool, free CDR and stacks of passives. That’s the crux of Darktides balance issue. Their current fundamental balance is literally so bad that you can’t actually add any interesting challenge. Havoc 40 is actually a complete joke compared to Weaves, just as a sidenote.